Portugal has developed a specific culture while being influenced by various civilizations that have crossed the Mediterranean and the European continent, or were introduced when it played an active role during the Age of Discovery. Portuguese literature, one of the earliest Western literatures, developed through text and song. Until 1350, the Portuguese-Galician troubadours spread their literary influence to most of the Iberian Peninsula. Gil Vicente (ca. 1465 - ca. 1536), was one of the founders of both Portuguese and Spanish dramatic traditions.
Adventurer and poet Luís de Camões (ca. 1524–1580) wrote the epic poem The Lusiads, with Virgil's Aeneid as his main influence. Modern Portuguese poetry is rooted in neoclassic and contemporary styles, as exemplified by Fernando Pessoa (1888–1935). Modern Portuguese literature is represented by authors such as Almeida Garrett, Camilo Castelo Branco, Eça de Queiroz, Sophia de Mello Breyner Andresen, and António Lobo Antunes. Particularly popular and distinguished is José Saramago, winner of the 1998 Nobel Prize for literature.

Portuguese music encompasses a wide variety of genres. The most renowned is fado, a melancholy urban music, usually associated with the Portuguese guitar and saudade, or longing. Coimbra fado, a unique type of fado, is also noteworthy. Internationally notable performers include Amália Rodrigues, Carlos Paredes, José Afonso, Mariza, Carlos do Carmo, Mísia, and Madredeus. One of the most notable Portuguese musical groups outside the country, and specially in Germany, is the goth-metal band Moonspell. In addition to fado and folk, the Portuguese listen to pop and other types of modern music, particularly from North America and the United Kingdom, as well as a wide range of Portuguese and Brazilian artists and bands. Bands with international recognition include Blasted Mechanism and The Gift, both of which were nominated for an MTV Music Award. Portugal has several summer music festivals, such as Festival Sudoeste in Zambujeira do Mar, Festival de Paredes de Coura in Paredes de Coura, Festival Vilar de Mouros near Caminha, and Rock in Rio Lisboa and Super Bock Super Rock in Lisbon. Out of the summer season, Portugal has a large number of festivals, designed more to an urban audience, like Flowfest or Hip Hop Porto. Furthermore, one of the largest international Goa trance festivals takes place in central Portugal every two years, and the student festivals of Queima das Fitas are major events in a number of cities across Portugal. In the Classical music domain, Portugal is represented by names as the pianist Maria João Pires, and in the past by the great cellist Guilhermina Suggia. Notable composers include Luís de Freitas Branco and his student Joly Braga Santos, and Fernando Lopes-Graça. Portuguese cinema has a long tradition, reaching back to the birth of the medium in the late 19th century. Portuguese film directors such as Arthur Duarte, António Lopes Ribeiro, Manoel de Oliveira, António-Pedro Vasconcelos, João Botelho and Leonel Vieira, are among those that gained notability. Noted Portuguese film actors include Joaquim de Almeida, Maria de Medeiros, Diogo Infante, Soraia Chaves, Vasco Santana, Ribeirinho, and António Silva, among many others. It has also a rich history as far as painting is concerned. The first well-known painters date back to the XV century – like Nuno Gonçalves - were part of the Gothic painting period. José Malhoa, known for his work Fado, and Columbano Bordalo Pinheiro (who painted the portraits of Teófilo Braga and Antero de Quental) were both references in naturalist painting.

The 20th century saw the arrival of Modernism, and along with it came the most prominent Portuguese painters: Amadeo de Souza-Cardoso, who was heavily influenced by French painters, particularly by the Delaunays. Among his best known works is Canção Popular a Russa e o Fígaro. Another great modernist painter/writer was Almada Negreiros, friend to the poet Fernando Pessoa, who painted his (Pessoa’s) portrait. He was deeply influenced by both Cubist and Futurist trends. Prominent international figures in visual arts nowadays include painters Vieira da Silva, Júlio Pomar, and Paula Rego.

Traditional architecture is distinctive. Modern Portugal has given the world renowned architects like Eduardo Souto de Moura, Álvaro Siza Vieira and Gonçalo Byrne. Internally, Tomás Taveira is also noteworthy.

Since the 1990s, Portugal has increased the number of public cultural facilities, in addition to the Calouste Gulbenkian Foundation established in 1956 in Lisbon. These include the Belém Cultural Center in Lisbon, Serralves Foundation and the Casa da Música, both in Porto, as well as new public cultural facilities like municipal libraries and concert halls which were built or renovated in many municipalities across the country.